Welcome to part seven of our blog series and your journey to understanding and protecting your DNA, reducing cancer risk, and passing on healthy genes to your children!

In the previous post we learned about magnesium’s role in preventing and mitigating two major forms of cellular and DNA damage: cellular calcium buildup and inflammation.

Today we take a look at how you need magnesium to protect your DNA from the third major form of DNA damage: oxidative stress. (You can find all the scientific literature for this post at iMag library’s DNA section.)


Oxidative Stress:

In the last post we learned that magnesium protects your cells and DNA from inflammation and calcification. Today we learn how it helps prevent the single most destructive form of cellular and DNA damage: oxidative stress.

Oxidative stress is the physical destruction of your cells, DNA and body. Oxidative stress occurs as a result of the creation of highly reactive oxygen-based molecules called free radicals.

These molecules are highly reactive because their electric charge has been disturbed and they have a powerful tendency to steal electrons from surrounding molecules such as mitochondria, cell membranes, and DNA. This can cause a chain reaction of molecular destruction and imbalance in the cell, which is extremely damaging to your DNA.

magnesium & genetics 7 - magnesium makes antioxidants to battle free radicals

We generally experience free radical production and the resulting oxidative stress from two different sources in our body:

  1. As a natural byproduct of your cells’ energy production.
  2. As a result of the toxic build-up of iron in your cells (much more potent and damaging).

Your body has its own mechanism for both fighting and preventing excess free radicals and their resulting oxidative damage. The first method is via the production of powerful helper molecules called antioxidants.

These antioxidants neutralize free radicals by giving them the extra electron they need, thus restoring their equilibrium and alleviating their reactivity. While we may acquire decent amounts of antioxidants from foods such as raw fruits and vegetables, our body make far more antioxidants than anything we can ingest from food sources. How is magnesium involved? 

It plays a key role in producing two of your body’s most potent antioxidants:

1. Glutathione – this is the human body’s most abundant antioxidant. It is made primarily in your liver and magnesium is needed for both its production and its recycling to keep its levels sufficient for battling free radicals.

2. Melatonin –  This molecule is widely popular for its sleep inducing effects, however it has extremely protective and antioxidant effects as well. Melatonin production also requires magnesium.


Simply put, magnesium helps make the antioxidant molecules your body needs to combat free radicals and the oxidative damage they bring about. Now let’s look at how magnesium helps prevent the second, more damaging source of free radicals:


Iron Toxicity & Massive Oxidative Stress

Magnesium also prevents the toxic build-up of iron in your cells – which is a much more potent form of oxidative stress. This is because excess, unbound iron atoms inside your cells stimulate a dangerous chemical reaction called the fenton reaction.

The fenton reaction produces the body’s most damaging free radical: the hydroxyl radical.

Magnesium prevents the creation of the hydroxyl radical by limitting the amount of unbound iron atoms that buildup in your cells. It does this via its role in creating the enzyme called ceruloplasmin:

Ceruloplasmin: the enzyme that loads free iron onto your blood’s oxygen-carrying molecules, preventing cellular iron toxicity and DNA damage.

Ceruloplasmin keeps iron from building up in your cells by instead attaching the iron to your blood’s oxygen-carrying molecules where it belongs.  If you’re low on magnesium, you may be low in ceruloplasmin, which means many of your cells and their DNA are experiencing damage from oxidative stress caused by iron toxicity and increased rates of the fenton reaction.

The worst part is that this excess iron is not detectable by standard testing methods used by the medical establishment. That’s because they only test iron in the blood, not the cells, and they don’t even test for ceruloplasmin levels.



Oxidative stress causes cellular and DNA damage which can lead to most major debilitating diseases, as well as passing on damaged DNA to your baby.  Furthermore magnesium deficiency has now become a silent epidemic that affects over 90% of people. To learn about why it’s so common, and how you can test your magnesium, read our magnesium basics series.

To see why so many people prefer iMag’s pure natural magnesium products to safely restore their magnesium levels and help protect their DNA, click here.

We’ll see you in the next and final post where we review our entire journey about understanding and boosting your DNA health for a better life for you and your children!

Related Posts:

Magnesium & DNA Health Part 6: Magnesium Protects Your DNA from Inflammation

Magnesium & DNA Health Part 8: Magnesium Is Your DNA’s Master Nutrient

Related Products:

iMag: World’s Purest

iMag is literally the world’s purest all natural magnesium supplement, from the European Zechstein Mineral Formation.

Click here to learn about it’s superior transdermal delivery systemfaster and safer than pills.

Click here to learn why it’s the best molecular form of magnesium for your body.

Watch out for fake Zechstein magnesium! Learn more here!


Anything not referenced/cited here can be found on iMag Library (magnesiumhealth.org). This is our sister website that we created for you with all the scientific literature about magnesium and the human body.

(We assume no responsibility and/or credit for any of the graphics used in this post. All credit goes to the various and individual creators of graphic and visual content.)